There … Hoping for good results! Seems like the Vitamin E is likely an essential piece. My father has SCLC and is receiving chemotherapy. 2018 Aug 9;8(1):11926. doi: 10.1038/s41598-018-30158-6. Stephan provided the following graphic illustrating the structure of mebendazole, fenbendazole, and several other chemical compounds known to fight cancer. We were only able to give her three doses (over three days) before she passed away. 728 posts. The truth of the matter is cancer is scary. All are welcome. /r/lungcancer is a place for stories, advice, etc. Fenbendazole did this by inhibition of an enzyme called hexokinase. Fenbendazole’s ability to preferentially kill of malignant cells without harming healthy cells is another of its proposed properties. Very curious. Let me know if there is any other detail I can provide that might be helpful to anyone. You may have to register before you can post: click the register link above to proceed. Glioblastoma multiforme (GBM), which has been classified as a grade IV astrocytoma, is a highly aggressive tumor that invades early into surrounding brain tissues, making cure via surgical resection almost impossible. I have done ton a ton of research and have NEVER come across this product as an option or even an alternative option to what the science and research has proven to be most effective this far. The only real side effects that I have had was some nausea, which may of may not have come from the Fenbendazole. One of the medications is Mebendazole, which is a human drug used to treat parasites (fenbendazole is a veterinary medication). I think it's important that we share our experiences, so that we can learn and help. My mum is in a similar situation.. Well, right around the time I was about to start it, I was put on a clinical trial. In fact, it can’t afford a cure. In the same group of drugs as Mebendazole, a group called benzimidazoles, there is another anti-worm drug called Fenbendazole. Good luck, I hope it works for you! He also takes Vit E as the research shows that Vit E and Fenbendazole worked better on prostate cancer. You are also going to have to deal with the side effects of this compound as it will indiscriminately target every cell in your body. Fenbendazole - Cancer Support Group has 5,387 members. Regardless, it was manageable with Zofran or Compazine. Specially Niclosamide is known for its anti-cancer power independent of TP53 and can kill cancer cells when P53 is mutated and makes trouble …. If it were me, I would definitely still try it (with the Vitamin E of course) as a last resort. Hi, just wanted to see if you had any updates on this. Press J to jump to the feed. "AACR: Merck's Keytruda, up for new FDA nod, spurs lengthy responses in small cell lung cancer". Possibly a decrease in kidney function as well at the time. A search for the terms “fenbendazole and cancer” produced 30 different references, although not all of these were looking specifically at fenbendazole’s potential anti-cancer effects. People with severe liver or kidney failure have lower medication excretion rates, therefore, fenbendazole can accumulate and cause unexpected side-effects. Find communities you're interested in, and become part of an online community! Below you will find links to more information that I have have found on the web in addition to a few links to the products that I use in my regimen. Original Poster. It also interferes with cancer cells abilities to use glucose. "Fenben acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways.". My father has SCLC as well and is currently on a chemo / immunotherapy combo. This reddit is for the discussion of cancer, cancer related news, stories of survival, stories of loss and everything else associated with the … Clinical trials look at new ways to prevent, detect, or treat disease. She did lose her voice shortly after taking her first dose of fenbendazole, but honestly that could have just been the fever. One sachet per day for 3 days then 4 off. They seem to be having some success. They have found that a group of medications used to treat parasitic diseases or helminthic manifestations can, in fact, help cancer patients. So, researchers tested the effect of fenbendazole on glucose uptake in human cancer cells. However, during fenbendazole treatment at our institution, an established human lymphoma xenograft model in C.B-17/Icr-prkdcscid … Procedure: Cats were randomly assigned to 1 of 3 treatment groups or a control group (n = 7/group). Discussion. Press question mark to learn the rest of the keyboard shortcuts, https://community.breastcancer.org/forum/8/topics/871246?page=7. Pregnant Dogs: A slightly altered dosage of 25 mg/kg fenbendazole may be used when treating pregnant dogs. There is some promising evidence in studies with mice and rats re: enhancing the effectiveness of chemo in treating breast cancer. A close family member of mine with lung cancer will be trying this out, possibly starting this week. One packet of Panacur C is 222 mg of Fenbendazole and 778 mg filler. It's from the clinical data. Tuesday 18th June 2019. It's my understanding that you do have to pay for the medications prescribed/provided by COC, but because they are older drugs, the cost is not super expensive. The first issue is the bulk. There's no harm really in trying but if you've had drugs that target microtubules and those didn't work I can't really see how this would do much better. bongtom. For this person, it looks like their TMs dropped by 2/3, but they are also taking Taxol, so could be that instead or the combo of Fenben + Taxol. Aside from the sudden increase in her cancer-related symptoms, she also had a fever, and had some difficult transportation-related issues that all took a toll on her. Written by dtcdirector May 14, 2020. Background/aims: To evaluate the anticancer activity of fenbendazole, a widely used antihelminth with mechanisms of action that overlap with those of the hypoxia-selective nitroheterocyclic cytotoxins/radiosensitizers and the taxanes. I'm trying it, have done one round so far. Have any of you tried it? Citation Dogra, K et al. Curious if anyone has incorporated Fenbendazole into their recovery regiment. Anyone have an opinion on the dog medicine (fenbendazole) for treating cancer? Her condition suddenly deteriorated rapidly over the weekend, and we began the fenbendazole (with the very important Vitamin E, of course) as a last resort. You can see how close they are. Thank you for visiting FenBenForum.com. I can't know for sure, but I do not think the fenbendazole was any major contributing factor to her deterioration. Fenbendazole, is a drug used typically not for humans like Mebendazole, but for … Diet containing the anthelminthic fenbendazole is used often to treat rodent pinworm infections because it is easy to use and has few reported adverse effects on research. I'm not responding to chemo and they say it is terminal so I'm trying this. Fenbendazole is a drug used for parasite and anti-worm treatments in animals. I personally do not care for the forum format. The longest one started maybe a five weeks ago and others are just beginning. But I am not a doctor, so take my .02 with a grain of salt. The clinical trials on this list are studying Mebendazole. If you have animals, then you’ve definitely heard of Fenbendazole. If this is your first visit, be sure to check out the FAQ by clicking the link above. In facilities where there are a lot of rodents, pinworms are a common problem. Then, by trial and error, they determined that the related drug mebendazole—which has been used for the last 60 years to treat parasites in the human gastrointestinal tract—might also hold potential for stalling glioblastoma. I wanted to find out if this protocol helped you? Reply Reply Author. Refrain from fighting, begging, and advertising. Some others are up for results reporting soon. I hope you’re okay. Clinical trials are research studies that involve people. Only one person (see page 16 - snooky1954) so far has had any results to report, and this is only for blood tumor markers, so not much in the way of robust supportive evidence. Hi everyone! I will post more information next week when I have more evidence that Fenbendazole is working. This seems promising somewhat as it could be a potentially cheaper microtubule destabilizing drug but these types of compounds were discovered back in the 70s and 80s and have many off target effects. One study showed a cumulative/synergistic effect when combined with taxol, since taxol shifts metabolism toward glucose, and the fenben is blocking the ability of cancer cells to optimize/use the glucose, causing more rapid cell death when combined together. Since he has been on the Fenbendazole, the swelling in his legs is gone and they are back to normal. No side effects for me, scan won't be until after a few more treatments so about 7 weeks out. Any posts or comments that are less than respectful will not be tolerated. Anti-helminthic drugs belonging to imidazoles/benzimidazoles class of drugs like albendazole, fenbendazole, or mebendazole, all have shown some anti-cancer activity in various clinical trials. For the last couple of days I have been glued to the internet researching drugs and current clinical trials. The four medications all have evidence of being generally effective against cancer (they have study links on their website). What are your thoughts regarding Fenbendazole? The data are summarised and discussed in relation to suggested mechanisms of action. Here is an article about a man who took medication for dog parasites/dewormer and he believes it helped to cure his stage iv cancer. Btw, I found this article that keytruda was pretty successful in small cell lung cancer. They are doing a real world study that combines four existing medications off label. Based on the evidence presented, it is proposed that … Press question mark to learn the rest of the keyboard shortcuts. https://community.breastcancer.org/forum/8/topics/871246?page=7. An in-vitro test applying vitamin E succinate and/or fenbendazole against prostate cancer cells found that fenbendazole inhibited proliferation but did so even better when combined with vitamin E succinate. I figure it's like being on a trial drug. Cats in the treatment groups were given fenbendazole at a dosage of 50, 150, or 250 mg/kg, PO, every 24 hours for 9 days; control cats were given a placebo. HIs energy has increased and he feels much better. Up to 5 % of people can experience stomach discomfort or diarrhea when taking large quantities of fenbendazole with no breaks. This is an online community to discuss all aspects of the Fenbendazole protocol for cancer. ... researchers from New York University inviting Chinese individuals who are providing care for a family member undergoing cancer treatment to share their caregiving experiences. Also using frankincense topically as well as diffusing it. Update. https://www.nature.com/articles/s41598-018-30158-6?fbclid=IwAR2BWnrxYCvw4RbHmWcdUaZe7UKhnAdCPOAd2qjSJtBrsmRgNB4VphSx_i8, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687140/?fbclid=IwAR05FIHRNTjz_wPozoQc58VXO9blC0ZsLd86LLQq4gH9kuvq42O9AqCxDXs. At that point, I'm sure the fenbendazole didn't help either... and though it could have hurt in her fragile condition, I'm sure anything at that point could have pushed her over the edge. More Information. All trials on the list are supported by NCI.. NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. What dosage of fenben? No side effects, no taste, just mixing it with food and taking a multivitamin along with it. There are much more promising clinical trials than this. This drug is a dog dewormer that is safe for human use. I started the protocol using Panacur C. That was fine to start out with, but there were some issues with it. I'm a little nervous to do it with my current treatment. Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways Sci Rep . What Is Fenbendazole and How Can It Affect Cancer Treatment? Here are a couple links to info. It is a common drug for veterinary use.… 2 Comments. I feel like I'm running out of options and am getting desperate. https://www.odditycentral.com/news/man-claims-cheap-dog-deworming-medicine-cured-his-terminal-cancer.html. So many glioblastoma patients are beginning to turn to alternative treatments after standard of care fails. Fenbendazole for cancer treatment . Scot is willing to do anything to live. " Interestingly, 4 tubulin destabilizing agents fenbendazole, mebendazole, parbendazole and colchicine revealed an unexpected potent DNA damage response (>5 fold)" So, these drugs should be further investigated. Desperate times call for drastic measures. Fenbendazole 3 days on, 4 days off.My name is Scot Pekarek. And how often are you taking it? Animals: 28 six- to seven-month old domestic short-hair cats. Last week we had to admit her to the ER because as we now know, a series of small brain tumors are taking away her ability to walk right, tell time, sleep, think, see etc. I have no control over the content on any of the linked sites. This study focused on tumor growth and how the drug affects it. Press J to jump to the feed. In this study, Fenbendazole alone did not have an inhibitory effect. The paper on KRAS mutated lung cancer (screeining in cell lines) Quick update - sadly, my relative passed away (peacefully, we think) before we could figure out whether it would help her or not. Stephan Stahl. Also, note that the research seems to suggest that fenbendazole would need to be used in conjunction with certain vitamin supplements. Searching the literature, they found reports that fenbendazole had been shown to inhibit cancer growth. Hi, I hope you’re feeling better. The last thing the cancer industry needs is a cure. Just curious, why does this get downvoted?

Dosage: Each box includes treatment for 1 Dog. Keep us posted. What is there to lose? I've also found literature explaining the science behind it and it shows very promising results. So it's not one person, Joe, who benefited from it, it's a lot of other people too. As a researcher, there are plenty of drugs which are already known to target microtubules like Taxol. Significantly, there are also two case reports of anti-cancer activity in humans. Please consider the Vitamin E. Seems like that might be an essential part. Have you looked at Care Oncology Clinic? I'm not doing his whole protocol, just the 3 on/4 off with fenben. I have Brain Cancer (Grade 2 Glioma). Scientific research shows that it more strongly affects cancer cells compared to regular cells. I'll keep you posted on how it goes. This community at this link is trying it together. ... help Reddit App Reddit coins Reddit premium Reddit gifts. Have you seen any results from taking this, positive or negative? Doses should be divided accordingly in this situation. The anti-worm drug Fenbendazole has anti-cancer potential. The last thing the cancer industry needs is a cure. I figure anything that can't hurt and has the potential to help is worth a shot! Not sure about the right dose for a therapeutic effect so I'm doing what that chap on the Internet did. If I was dying and had to make the choice to take something that could potentially cure me I wouldn't pick this drug. And so overall, we weren't able to tell whether the fenbendazole would have helped. Mebendazole, a well-known anti-helminthic drug in wide clinical use, has anti-cancer properties that have been elucidated in a broad range of pre-clinical studies across a number of different cancer types. 43 months. The original group is being turned off and moved to a forum. That filler is a combination of milk sugar, cornstarch and calcium. Definitely make sure you get the Vitamin E. I'm guessing that's in your multivitamin, though. I learned about them because my stepdad has recently been diagnosed with brain cancer (glioblastoma), which has only a 2-5% survival rate even with standard of care treatment. Two different type of cancer cells, H460 and A549 cells, were treated with fenbendazole. Objective: To evaluate the safety of fenbendazole in domestic cats. Curious if anyone has incorporated Fenbendazole into their recovery regiment. Reddit is a network of communities based on people's interests. To start viewing messages, select the forum that you want to visit from the selection below. Fenbendazole & Cancer My Experience with Panacur C and Colon Cancer. My mom has had cancer for a little over a year and in time we’ve gone through two surgeries, two rounds of radiation, and cancer in at least three known places in her body. This becomes a … Fenbendazole & Cancer My Experience with Panacur C and Colon Cancer. 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